Cardiac tissue engineering: characteristics of in unison contracting two- and three-dimensional neonatal rat ventricle cell (co)-cultures.

@article{Luyn2002CardiacTE,
  title={Cardiac tissue engineering: characteristics of in unison contracting two- and three-dimensional neonatal rat ventricle cell (co)-cultures.},
  author={M J A van Luyn and Ren{\'e} A. Tio and X J Gallego y van Seijen and Jos{\'e}e A. Plantinga and Lou F. M. H. de Leij and Mike J L Dejongste and Pauline B van Wachem},
  journal={Biomaterials},
  year={2002},
  volume={23 24},
  pages={4793-801}
}
Patients with heart failure have, in spite of improved palliative therapies, bad prognosis. Cardiac tissue engineering by use of a temporary bioscaffold and cardiomyocytes may help to find answers for future treatments in heart failure. For that purpose two neonatal rat heart ventricular cell fractions were obtained after a gradient cell separation. Time related characteristics of Fractions I and II were established in two-dimensional (2-D) and three-dimensional (3-D) cell cultures. The 3-D… CONTINUE READING

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