Cardiac sympathovagal modulation evaluated by short-term heart interval variability is subtly impaired in Alzheimer's disease.

@article{Toledo2008CardiacSM,
  title={Cardiac sympathovagal modulation evaluated by short-term heart interval variability is subtly impaired in Alzheimer's disease.},
  author={Maria Alice de Vilhena Toledo and Luiz Fernando Junqueira},
  journal={Geriatrics & gerontology international},
  year={2008},
  volume={8 2},
  pages={109-18}
}
AIM Alzheimer's disease affects several nervous structures involved with the autonomic nervous system. Therefore, the still scarce evaluation of the cardiac autonomic function in this disease is of great functional, clinical, prognostic and therapeutic relevance. METHODS Time- and frequency-domain variability of 5-min R-R interval series in supine and standing positions was comparatively evaluated in 22 Alzheimer's disease subjects, aged 60-87 years (mean +/- standard error of the mean, 79.6… CONTINUE READING

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