Cardiac surgery as a cause of acute kidney injury: pathogenesis and potential therapies.

@article{Rosner2008CardiacSA,
  title={Cardiac surgery as a cause of acute kidney injury: pathogenesis and potential therapies.},
  author={Mitchell H. Rosner and Didier Portilla and Mark Douglas Okusa},
  journal={Journal of intensive care medicine},
  year={2008},
  volume={23 1},
  pages={3-18}
}
Cardiopulmonary bypass surgery occurs in nearly 1 million patients per year. Acute kidney injury requiring dialysis can occur in up to 1% of these patients. The development of acute kidney injury is associated with substantial morbidity and mortality independent of all other factors, and many patients are left dependent on dialysis therapies. The pathogenesis of acute kidney injury involves multiple pathways. Hemodynamic, inflammatory, and nephrotoxic factors are involved and overlap each other… CONTINUE READING