Cardiac surgery: myocardial energy balance, antioxidant status and endothelial function after ischemia-reperfusion.

@article{Carlucci2002CardiacSM,
  title={Cardiac surgery: myocardial energy balance, antioxidant status and endothelial function after ischemia-reperfusion.},
  author={Filippo Carlucci and Antonella Tabucchi and Bonizella Biagioli and Frederick Simeone and Sabino Scolletta and Francesca Rosi and Enrico Marinello},
  journal={Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie},
  year={2002},
  volume={56 10},
  pages={483-91}
}
Myocardial and endothelial damage is still a widely debated problem during the ischemia-reperfusion sequence in heart surgery. We evaluated myocardial purine metabolites, antioxidant defense mechanisms, oxidative status and endothelial dysfunction markers in 14 patients undergoing coronary artery by-pass graft (CABG). Heart biopsies were taken before aortic cross-clamping (t1), before clamp removal (t2) and 30 min after reperfusion (t3); perchloric extracts of the tissue were analyzed for… CONTINUE READING