Cardiac support device modifies left ventricular geometry and myocardial structure after myocardial infarction.

@article{Blom2005CardiacSD,
  title={Cardiac support device modifies left ventricular geometry and myocardial structure after myocardial infarction.},
  author={Aaron S. Blom and Rupak Mukherjee and James J. Pilla and Abigail S. Lowry and William M. Yarbrough and Joseph T. Mingoia and Jennifer W. Hendrick and Robert E. Stroud and Julie E. McLean and John D Affuso and Robert C. Gorman and Joseph H. Gorman and Michael A. Acker and Francis G. Spinale},
  journal={Circulation},
  year={2005},
  volume={112 9},
  pages={1274-83}
}
BACKGROUND Whether mechanical restraint of the left ventricle (LV) can influence remodeling after myocardial infarction (MI) remains poorly understood. This study surgically placed a cardiac support device (CSD) over the entire LV and examined LV and myocyte geometry and function after MI. METHODS AND RESULTS Post-MI sheep (35 to 45 kg; MI size, 23+/-2%) were randomized to placement of the CorCap CSD (Acorn Cardiovascular, Inc) (MI+CSD; n=6) or remained untreated (MI only; n=5… CONTINUE READING