Cardiac spinal deafferentation reduces the susceptibility to sustained ventricular tachycardia in conscious rats.

@article{Lujan2011CardiacSD,
  title={Cardiac spinal deafferentation reduces the susceptibility to sustained ventricular tachycardia in conscious rats.},
  author={Heidi L. Lujan and Sandhya Krishnan and Stephen E DiCarlo},
  journal={American journal of physiology. Regulatory, integrative and comparative physiology},
  year={2011},
  volume={301 3},
  pages={R775-82}
}
The response to myocardial ischemia is complex and involves the cardio-cardiac sympathetic reflex. Specifically, cardiac spinal (sympathetic) afferents are excited by ischemic metabolites and elicit an excitatory sympathetic reflex, which plays a major role in the genesis of ventricular arrhythmias. For example, brief myocardial ischemia leads to ATP… CONTINUE READING