Cardiac repair using chitosan-hyaluronan/silk fibroin patches in a rat heart model with myocardial infarction.

@article{Chi2013CardiacRU,
  title={Cardiac repair using chitosan-hyaluronan/silk fibroin patches in a rat heart model with myocardial infarction.},
  author={Nai-Hsin Chi and Ming-Chia Yang and Tze-Wen Chung and Nai-Kuan Chou and Shoei-shen Wang},
  journal={Carbohydrate polymers},
  year={2013},
  volume={92 1},
  pages={591-7}
}
The cardiac repair of myocardial infarction (MI) hearts of rats using chitosan-hyaluronan/silk fibroin (chitosan-HYA/SF) cardiac patches was examined after eight weeks of implantation. Rats with implantations of chitosan-HYA/SF patches (CHS group) significantly (P<0.05) reduced the dilation of the inner diameter of left ventricle (LV) (4.27 ± 0.29 mm), increased wall thickness of LV (1.5 ± 0.13 mm) and improved the fractional shortening of LV of hearts (LVFS) (42.8 ± 2.4%) compared with those… CONTINUE READING
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