Cardiac progenitor cell commitment is inhibited by nuclear Akt expression.

Abstract

RATIONALE Stem cell therapies to regenerate damaged cardiac tissue represent a novel approach to treat heart disease. However, the majority of adoptively transferred stem cells delivered to damaged myocardium do not survive long enough to impart protective benefits, resulting in modest functional improvements. Strategies to improve survival and… (More)
DOI: 10.1161/CIRCRESAHA.110.237156

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