Cardiac production of C-type natriuretic peptide in heart failure.

  title={Cardiac production of C-type natriuretic peptide in heart failure.},
  author={Silvia del Ry and Maristella Maltinti and Marcello Piacenti and Claudio Passino and Michele Emdin and Daniela Giannessi},
  journal={Journal of cardiovascular medicine},
  volume={7 6},
BACKGROUND C-type natriuretic peptide production by the heart in patients with chronic heart failure has recently been demonstrated by measuring the difference in C-type natriuretic peptide plasma levels between the aortic root and coronary sinus samples. To assess this previous relevant observation, we re-evaluated the cardiac production of C-type natriuretic peptide, thus increasing the total number of patients studied. In light of the difficulty in recruiting patients with these… CONTINUE READING