Cardiac physiology and clinical efficacy of dietary fish oil clarified through cellular mechanisms of omega-3 polyunsaturated fatty acids

@article{McLennan2014CardiacPA,
  title={Cardiac physiology and clinical efficacy of dietary fish oil clarified through cellular mechanisms of omega-3 polyunsaturated fatty acids},
  author={Peter L. McLennan},
  journal={European Journal of Applied Physiology},
  year={2014},
  volume={114},
  pages={1333-1356}
}
  • P. McLennan
  • Published 4 April 2014
  • Biology, Medicine
  • European Journal of Applied Physiology
Reduced cardiac mortality and morbidity have long been observed in association with omega-3 long chain polyunsaturated fatty acids (LC-PUFA), eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) from fish consumption, without clear physiological explanation. This review seeks to identify mechanisms of action based on evidence: of physiological effects, active components and effective intakes. Fish oil pleiotropic effects reveal actions that are either intrinsic: effects on cardiac… 
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