Cardiac performance and mass in adults with hypopituitarism: effects of one year of growth hormone treatment.

@article{Valcavi1995CardiacPA,
  title={Cardiac performance and mass in adults with hypopituitarism: effects of one year of growth hormone treatment.},
  author={Roberto Valcavi and Oscar Gaddi and Michele Zini and M. Iavicoli and U Mellino and Italo Portioli},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1995},
  volume={80 2},
  pages={659-66}
}
We studied the effects of GH administration on myocardial structure and function in 20 patients with hypopituitarism (14 males and 6 females; mean +/- SE age, 47.2 +/- 2.6 yr; range, 31-59 yr) developed in adulthood because of pituitary or parapituitary tumors. All patients had GH deficiency (GHD), as assessed by a GH response of less than 4 micrograms/L to a standard insulin tolerance test (0.05 U kg, iv) and the combined pyridostigmine (120 mg, orally, at -60 min) plus GHRH (1 microgram/kg… CONTINUE READING