Cardiac myosin binding protein C.

@article{Winegrad1999CardiacMB,
  title={Cardiac myosin binding protein C.},
  author={Saul Winegrad},
  journal={Circulation research},
  year={1999},
  volume={84 10},
  pages={1117-26}
}
Myosin binding protein C (MyBP-C) is one of a group of myosin binding proteins that are present in the myofibrils of all striated muscle. The protein is found at 43-nm repeats along 7 to 9 transverse lines in a portion of the A band where crossbridges are found (C zone). MyBP-C contains myosin and titin binding sites at the C terminus of the molecule in all 3 of the isoforms (slow skeletal, fast skeletal, and cardiac). The cardiac isoform also includes a series of residues that contain 3… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 89 extracted citations

Designing heart performance by gene transfer.

Physiological reviews • 2008
View 20 Excerpts
Highly Influenced

Thick Filament Proteins and Performance in Human Heart Failure

Heart Failure Reviews • 2005
View 5 Excerpts
Highly Influenced

Myosin-binding protein C displaces tropomyosin to activate cardiac thin filaments and governs their speed by an independent mechanism.

Proceedings of the National Academy of Sciences of the United States of America • 2014
View 4 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 79 references

Similar Papers

Loading similar papers…