Cardiac morphology and function in senescent rats: gender-related differences.

  title={Cardiac morphology and function in senescent rats: gender-related differences.},
  author={Daniel E. Forman and Antonio Cittadini and Gohar Azhar and Pamela Sylvia Douglas and Jeanne Y Wei},
  journal={Journal of the American College of Cardiology},
  volume={30 7},
OBJECTIVES We sought to better understand the effects of aging and gender on left ventricular (LV) structure and function. BACKGROUND Cardiovascular disease in older persons is associated with increased mortality and morbidity. The influence of gender on age-related cardiac changes is incompletely characterized. METHODS We studied 34 senescent, male and female, normotensive Fischer rats with transthoracic Doppler echocardiography and morphometric and histopathologic analyses. RESULTS Male… CONTINUE READING


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Carnitine palmitoyl transferase-I activity in the young and old mouse heart

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