Cardiac miR-133a overexpression prevents early cardiac fibrosis in diabetes

@inproceedings{Chen2014CardiacMO,
  title={Cardiac miR-133a overexpression prevents early cardiac fibrosis in diabetes},
  author={Shali Chen and Prasanth Puthanveetil and Biao Feng and Scot J Matkovich and Gerald W. Dorn and Subrata Chakrabarti},
  booktitle={Journal of cellular and molecular medicine},
  year={2014}
}
Diabetic cardiomyopathy is a cascade of complex events leading to eventual failure of the heart and cardiac fibrosis being considered as one of its major causes. miR-133a is one of the most abundantly expressed microRNAs in the heart. We investigated the role of miR-133a during severe hyperglycaemia. And, our aim was to find out what role miR-133a plays during diabetes-induced cardiac fibrosis. We saw a drastic decrease in miR-133a expression in the hearts of streptozotocin-induced diabetic… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 47 extracted citations

MiR-154 promotes myocardial fibrosis through β-catenin signaling pathway.

European review for medical and pharmacological sciences • 2018

Regulating microRNA expression: at the heart of diabetes mellitus and the mitochondrion.

American journal of physiology. Heart and circulatory physiology • 2018
View 1 Excerpt

References

Publications referenced by this paper.
Showing 1-10 of 24 references

The pathogenesis of myocardial fibrosis in the setting of diabetic cardiomyopathy

A Juan, JV Francisco
J Am Coll Cardiol • 2006
View 5 Excerpts
Highly Influenced

Similar Papers

Loading similar papers…