Cardiac metabolism in myocardial ischemia.

@article{Rosano2008CardiacMI,
  title={Cardiac metabolism in myocardial ischemia.},
  author={Giuseppe M. C. Rosano and Massimo Fini and Giuseppe Caminiti and G. Barbaro},
  journal={Current pharmaceutical design},
  year={2008},
  volume={14 25},
  pages={
          2551-62
        }
}
Myocardial ischemia occurs for a mismatch between blood flow and metabolic requirements, when the rate of oxygen and metabolic substrates delivery to the myocardium is insufficient to meet the myocardial energy requirements for a given myocardial workload. During ischemia, substantial changes occur in cardiac energy metabolism, as a consequence of the reduced oxygen availability. Some of these metabolic changes are beneficial and may help the heart adapt to the ischemic condition. However, most… CONTINUE READING
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