Cardiac leiomodin2 binds to the sides of actin filaments and regulates the ATPase activity of myosin

Abstract

Leiomodin proteins are vertebrate homologues of tropomodulin, having a role in the assembly and maintenance of muscle thin filaments. Leiomodin2 contains an N-terminal tropomodulin homolog fragment including tropomyosin-, and actin-binding sites, and a C-terminal Wiskott-Aldrich syndrome homology 2 actin-binding domain. The cardiac leiomodin2 isoform… (More)
DOI: 10.1371/journal.pone.0186288

Topics

7 Figures and Tables

Cite this paper

@inproceedings{Szatmri2017CardiacLB, title={Cardiac leiomodin2 binds to the sides of actin filaments and regulates the ATPase activity of myosin}, author={D{\'a}vid Szatm{\'a}ri and Be{\'a}ta Bugyi and Zolt{\'a}n Ujfalusi and L{\'a}szl{\'o} Grama and R{\'e}ka Dud{\'a}s and Mikl{\'o}s Nyitrai}, booktitle={PloS one}, year={2017} }