Cardiac isoenzyme methodology and the diagnosis of acute myocardial infarction.

  title={Cardiac isoenzyme methodology and the diagnosis of acute myocardial infarction.},
  author={Daniel L. Seckinger and Dr. A. V{\'a}zquez and P K Rosenthal and R C Mendizabal},
  journal={American journal of clinical pathology},
  volume={80 2},
In view of rapidly evolving technology, a thorough appreciation of the subtle nuances of isoenzyme analysis is mandatory in the selection of appropriate methods. The effectiveness of a given laboratory in diagnosing and monitoring ischemic heart disease is related to the sensitivity and specificity of the methods employed. The occurrence of variants of creatine kinase will decrease the specificity of some isoenzyme methods. This study compares the sensitivity and efficiency of four methods for… CONTINUE READING

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