Cardiac hypertrophy after transplantation is associated with persistent expression of tumor necrosis factor-alpha.

@article{Stetson2001CardiacHA,
  title={Cardiac hypertrophy after transplantation is associated with persistent expression of tumor necrosis factor-alpha.},
  author={Sonny J. Stetson and Alex Perez-Verdia and Wojciech Mazur and John Alan Farmer and Michael Martin Koerner and Donald G. Weilbaecher and Mark L. Entman and Miguel Angel Qui{\~n}ones and George Peter Noon and Guillermo Torre-Amione},
  journal={Circulation},
  year={2001},
  volume={104 6},
  pages={676-81}
}
BACKGROUND The mechanisms that contribute to cardiac allograft hypertrophy are not known; however, the rapid progression and severity of hypertrophy suggest that nonhemodynamic factors may play a contributory role. Tumor necrosis factor-alpha (TNF-alpha) is a cytokine produced in cardiac allografts and capable of producing hypertrophy and fibrosis; therefore, we suggest that TNF-alpha may play a contributory role. Accordingly, the aims of our study were to define the role of systemic… CONTINUE READING

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Restrictive physiology late after transplantation adversely affects survival. Circulation. 1997;96(suppl I):I-14

  • R Alvarez, D McNamara, B Bozkurt
  • 1997

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