Corpus ID: 10645032

Cardiac glycosides inhibit proliferation and induce apoptosis of human hematological malignant cells

@inproceedings{Xu2016CardiacGI,
  title={Cardiac glycosides inhibit proliferation and induce apoptosis of human hematological malignant cells},
  author={Yue-yi Xu and Juan Li and B. Chen and M. Zhou and Yi-Cheng Zeng and Q. Zhang and Yanting Guo and Jinhao Chen and J. Ouyang},
  year={2016}
}
Cardiac glycosides have been used to treat heart diseases for centuries. Recently, the emerging role of these compounds in cancer treatment is being noticed. Mounting evidences suggest that these steroid-like compounds have both anti-proliferation and pro-apoptosis effects on different human solid tumor cells. Our study mainly focuses on hematological malignant diseases. We took 19 different kind of hematological cells as research object. By calculating the IC50 and apoptosis rate of each cell… Expand

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