Cardiac fatty acid uptake and transport in health and disease.

  title={Cardiac fatty acid uptake and transport in health and disease.},
  author={Ger J. van der Vusse and M W T van Bilsen and Jan F. C. Glatz},
  journal={Cardiovascular research},
  volume={45 2},
Fatty acids are important energy donors for the healthy heart. These substrates are supplied to the myocardium bound to albumin to overcome their low solubility in aqueous solutions such as blood plasma. Transport from the microvascular compartment to the mitochondria inside the cardiomyocytes is most likely a combination of passive and protein-mediated diffusion. Alterations in tissue content of fatty acid-transport proteins may contribute to myocardial diseases such as the diabetic heart, and… CONTINUE READING


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A role for Sp and 1 myocytes of mice lacking the heart - type fatty acid - binding protein nuclear receptor transcription factors in a cardiac hypertrophic ( H - FABP ) gene

  • MN Sack, DL Disch, HA Rockman, DP Kelly
  • Circ Res
  • 1999

Abnormal diomyocyte gene expression

  • M VanBilsen, MM Vork, +5 authors MI Uusitupa
  • J Mol Cell Cardiol
  • 1999

Absent myocardial of the diabetic rat

  • EH Hwang, A Yamashita, H Takemori
  • Mol Cell Biochem
  • 1999

Binding of sulfosuccinimidyl fattycoding for proteins implicated in long - chain fatty acid uptake

  • CM Harmon, NA Abumrad
  • Int J acids to adipocyte membrane proteins…
  • 1999

Coordinate regulation up - regulation in diabetes

  • BD Jump, SD Clarke, A Thelen, M Liimatta
  • Biochem J
  • 1999

plasmic fatty acid-binding protein content in liver, heart and kidney

  • EH Hwang, A Yamashita, H Takemori
  • J Mol Cell Cardiol
  • 1999

, mutant of CD 36 is secreted and binds thrombospondin . Evidence for Glatz JFC . Uptake and metabolism of palmitate by isolated cardiaca single transmembrane domain

  • SF Pearce, J Wu, RL Silverstein, FA VanNieuwenhoven, G America, GJ VanderVusse
  • Eur J Cell Biol
  • 1998

Eicosanoid synthesis in car - regulation of metabolic processes : implications for cardiac metabo - diomyocytes : influence of hypoxia , reoxygenation , and polyunsatu - lism

  • M VanBilsen, GJ VanderVusse, RS Reneman, F Oudot, A Grynberg, JP Sergiel
  • Eur J Physiol
  • 1998

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