Cardiac energetics during ischaemia and the rationale for metabolic interventions.

@article{Stanley2001CardiacED,
  title={Cardiac energetics during ischaemia and the rationale for metabolic interventions.},
  author={William Stanley},
  journal={Coronary artery disease},
  year={2001},
  volume={12 Suppl 1},
  pages={S3-7}
}
Cardiac work is supported by high rates of combustion of carbon fuel and oxygen consumption. Fatty acids are the main fuel for the healthy heart, supplying approximately 60-80% of the energy. The balance of the energy comes from the oxidation of glucose and lactate. ATP is broken down to fuel contractile work. ATP is resynthesized in the mitochondria using energy from the oxidation of fatty acids, glucose, and lactate. Myocardial ischaemia dramatically alters fuel metabolism. Ischaemia occurs… CONTINUE READING

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