Cardiac diastolic dysfunction in high-fat diet fed mice is associated with lipotoxicity without impairment of cardiac energetics in vivo.

@article{Abdurrachim2014CardiacDD,
  title={Cardiac diastolic dysfunction in high-fat diet fed mice is associated with lipotoxicity without impairment of cardiac energetics in vivo.},
  author={D. Abdurrachim and J. {\vC}iapaitė and B. Wessels and M. Nabben and J. Luiken and K. Nicolay and J. Prompers},
  journal={Biochimica et biophysica acta},
  year={2014},
  volume={1842 10},
  pages={
          1525-37
        }
}
Obesity is often associated with abnormalities in cardiac morphology and function. This study tested the hypothesis that obesity-related cardiomyopathy is caused by impaired cardiac energetics. In a mouse model of high-fat diet (HFD)-induced obesity, we applied in vivo cardiac (31)P magnetic resonance spectroscopy (MRS) and magnetic resonance imaging (MRI) to investigate cardiac energy status and function, respectively. The measurements were complemented by ex vivo determination of oxygen… Expand
Cardiac function and intracellular Ca2+ handling proteins are not impaired by high-saturated-fat diet-induced obesity
Diastolic dysfunction in prediabetic male rats: Role of mitochondrial oxidative stress.
The effects of fatty acid composition on cardiac hypertrophy and function in mouse models of diet-induced obesity.
Cardiovascular magnetic resonance detects the progression of impaired myocardial perfusion reserve and increased left-ventricular mass in mice fed a high-fat diet
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 76 REFERENCES
Cardiac remodeling in a rat model of diet-induced obesity.
The role of dietary fatty acids in predicting myocardial structure in fat-fed rats
Gender-dependent effects of high-fat lard diet on cardiac function in C57Bl/6J mice.
Mitochondrial Energetics in the Heart in Obesity-Related Diabetes
...
1
2
3
4
5
...