Cardiac defects, morbidity and mortality in patients affected by RASopathies. CARNET study results.

@article{Calcagni2017CardiacDM,
  title={Cardiac defects, morbidity and mortality in patients affected by RASopathies. CARNET study results.},
  author={Giulio Calcagni and Giuseppe Limongelli and Angelo D'Ambrosio and Francesco Gesualdo and Maria Christina Digilio and Anwar Baban and Sonia Bernadette Albanese and Paolo Versacci and Enrica De Luca and Giovanni Battista Ferrero and Giuseppina Baldassarre and Gabriella Agnoletti and Elena Banaudi and Jan Marek and Juan Pablo Kaski and Giulia Tuo and M Giovanna Russo and Giuseppe Pacileo and Ornella Milanesi and Daniela Messina and Maurizio Marasini and Francesca Cairello and Roberto Formigari and Maurizio Brighenti and Bruno Dallapiccola and M Tartaglia and Bruno Marino},
  journal={International journal of cardiology},
  year={2017},
  volume={245},
  pages={92-98}
}
  • Giulio Calcagni, Giuseppe Limongelli, +24 authors Bruno Marino
  • Published 2017 in International journal of cardiology
  • DOI:10.1016/j.ijcard.2017.07.068
BACKGROUND RASopathies are developmental disease caused by mutations in genes encoding for signal transducers of the RAS-MAPK cascade. The aim of the present study was to provide a comprehensive description of morbidity and mortality in patients with molecularly confirmed RASopathy. METHODS A multicentric, observational, retrospective study was conducted in seven European cardiac centres participating to the CArdiac Rasopathy NETwork (CARNET). Clinical records of 371 patients with confirmed… CONTINUE READING