Cardiac cycle-dependent changes in aortic area and distensibility are reduced in older patients with isolated diastolic heart failure and correlate with exercise intolerance.

@article{Hundley2001CardiacCC,
  title={Cardiac cycle-dependent changes in aortic area and distensibility are reduced in older patients with isolated diastolic heart failure and correlate with exercise intolerance.},
  author={W. Gregory Hundley and Dalane W. Kitzman and Timothy M. Morgan and Craig A. Hamilton and Stephen N Darty and Kathryn P. Stewart and David M. Herrington and Kerry M. Link and William James Little},
  journal={Journal of the American College of Cardiology},
  year={2001},
  volume={38 3},
  pages={796-802}
}
OBJECTIVES The goal of this study was to determine if cardiac cycle-dependent changes in proximal thoracic aortic area and distensibility are associated with exercise intolerance in elderly patients with diastolic heart failure (DHF). BACKGROUND Aortic compliance declines substantially with age. We hypothesized that a reduction in cardiac cycle-dependent changes in thoracic aortic area and distensibility (above that which occurs with aging) could be associated with the exercise intolerance… CONTINUE READING