Cardiac contractility is not depressed in early canine endotoxic shock.

@article{Pinsky2000CardiacCI,
  title={Cardiac contractility is not depressed in early canine endotoxic shock.},
  author={Michael R. Pinsky and P. Martin Rico},
  journal={American journal of respiratory and critical care medicine},
  year={2000},
  volume={161 4 Pt 1},
  pages={1087-93}
}
We investigated effects of acute endotoxemia (Escherichia coli endotoxin, 1 mg/kg, intravenously) on left ventricular (LV) function in the first 4 h after induction of endotoxic shock in anesthetized canine preparations (n = 7 each, endotoxin and control groups). LV pressure and conductance (volume) catheters were used to construct pressure-volume loops. Transient inferior vena cava occlusion was used to rapidly and reversibly alter LV end-diastolic volume. LV contractility was assessed from… CONTINUE READING

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