Cardiac contractility and blood flow distribution following resuscitation with 7.5% hypertonic saline in anesthetized dogs.

Abstract

We examined the specific effects of 7.5% hypertonic saline (HTS) on myocardial performance and regional blood flow and compared the efficacies of HTS and lactated Ringer's solution (LR) for hypovolemic resuscitation. Studies were performed in anesthetized dogs subjected to rapid hemorrhage to decrease mean arterial pressure by 50% over 60 min. The animals… (More)

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