Cardiac chemical constant. Part II: Application to normal and abnormal left ventricular function.


A physiochemical parameter has been defined as KD, the cardiac chemical equilibrium dissociation constant, and represents the ratio of long units (extended sarcomeres) to short units (contracted sarcomeres) of a hypothetical mid-wall circumferential fibre. KD has been separately identified for three specific points in the cardiac cycle: end-diastole (KDED… (More)