Cardiac calcium pump inactivation and nitrosylation in senescent rat myocardium are not attenuated by long-term treadmill training.

Abstract

The senescent heart has decreased systolic and diastolic functions, both of which could be related to alterations in cardiac sarcoplasmic reticulum (SR) calcium (Ca(2+)) handling. The purpose of this study was to determine if SR protein content and rates of Ca(2+) release and uptake and ATPase activity are lower in the senescent (34-36 mo) Fisher 344×Brown… (More)
DOI: 10.1016/j.exger.2011.06.005

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@article{Thomas2011CardiacCP, title={Cardiac calcium pump inactivation and nitrosylation in senescent rat myocardium are not attenuated by long-term treadmill training.}, author={Melissa M. Thomas and Chris Vigna and Andrew C Betik and A Russell Tupling and Russell T. Hepple}, journal={Experimental gerontology}, year={2011}, volume={46 10}, pages={803-10} }