Cardiac autonomic receptors: effect of long-term experimental diabetes.

  title={Cardiac autonomic receptors: effect of long-term experimental diabetes.},
  author={Jamshid Latifpour and John Hugh McNeill},
  journal={The Journal of pharmacology and experimental therapeutics},
  volume={230 1},
The present study was undertaken to study the effects of long-term streptozotocin-induced diabetes on ventricular autonomic receptors. Left ventricle and lungs were removed from animals sacrificed either 3 or 6 months after streptozotocin administration (65 mg/kg). Diabetic rats were significantly smaller and had elevated serum glucose and reduced serum insulin values as compared with their age-matched controls. The alpha-1, beta adrenergic and muscarinic cholinergic receptors were identified… CONTINUE READING
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