Cardiac autonomic dysfunction in patients with Alzheimer disease: possible pathogenetic mechanisms.

@article{Giubilei1998CardiacAD,
  title={Cardiac autonomic dysfunction in patients with Alzheimer disease: possible pathogenetic mechanisms.},
  author={Franco Giubilei and Stefano Strano and Bruno Pietro Imbimbo and Paolo Tisei and Giovanni Calcagnini and Shiro Lino and Marco Frontoni and Massimo Santini and Cesare Fieschi},
  journal={Alzheimer disease and associated disorders},
  year={1998},
  volume={12 4},
  pages={356-61}
}
We studied a possible correlation between autonomic cardiac activity and the level of the red blood cell acetylcholinesterase (AChE) in patients with probable Alzheimer disease (AD). The influence of cholinesterase inhibitor treatment on this autonomic activity was evaluated. Twelve patients satisfying the NINCDS-ADRDA criteria of probable AD and 10 healthy controls were studied. Autonomic cardiac activity was evaluated by means of power spectral analysis (PSA) of heart rate variability (HRV… CONTINUE READING

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