Cardiac autonomic dysfunction in idiopathic REM sleep behavior disorder.

  title={Cardiac autonomic dysfunction in idiopathic REM sleep behavior disorder.},
  author={Ronald B. Postuma and Paola A Lanfranchi and H{\'e}l{\`e}ne Blais and Jean-François Gagnon and Jacques Y. Montplaisir},
  journal={Movement disorders : official journal of the Movement Disorder Society},
  volume={25 14},
More than 50% of persons with idiopathic REM sleep behavior disorder (RBD) will develop Parkinson's disease or Lewy body dementia. Symptom screens and metaiodobenzylguanine (MIBG)-scintigraphy suggest autonomic abnormalities in idiopathic RBD, but it is unclear whether autonomic abnormalities can predict neurodegenerative disease. From a cohort of 99 patients with idiopathic RBD, we selected those who developed parkinsonism or dementia. These were matched by age, sex, and follow-up duration to… CONTINUE READING