Cardiac and skeletal muscles show molecularly distinct responses to cancer cachexia.

@article{Shum2015CardiacAS,
  title={Cardiac and skeletal muscles show molecularly distinct responses to cancer cachexia.},
  author={Angie Man-Yee Shum and David Cho Yau. Fung and Susan M. Corley and Max C. McGill and Nicholas L. Bentley and Timothy C. Tan and Marc R. Wilkins and P. David Polly},
  journal={Physiological genomics},
  year={2015},
  volume={47 12},
  pages={
          588-99
        }
}
Cancer cachexia is a systemic, paraneoplastic syndrome seen in patients with advanced cancer. There is growing interest in the altered muscle pathophysiology experienced by cachectic patients. This study reports the microarray analysis of gene expression in cardiac and skeletal muscle in the colon 26 (C26) carcinoma mouse model of cancer cachexia. A total of 268 genes were found to be differentially expressed in cardiac muscle tissue, compared with nontumor-bearing controls. This was fewer than… CONTINUE READING
BETA
Tweets
This paper has been referenced on Twitter 2 times. VIEW TWEETS

Similar Papers

Loading similar papers…