Cardiac adipose tissue and atrial fibrillation: the perils of adiposity.

  title={Cardiac adipose tissue and atrial fibrillation: the perils of adiposity.},
  author={St{\'e}phane Nicolas Hatem and Alban Redheuil and Estelle Gandjbakhch},
  journal={Cardiovascular research},
  volume={109 4},
The amount of adipose tissue that accumulates around the atria is associated with the risk, persistence, and severity of atrial fibrillation (AF). A strong body of clinical and experimental evidence indicates that this relationship is not an epiphenomenon but is the result of complex crosstalk between the adipose tissue and the neighbouring atrial myocardium. For instance, epicardial adipose tissue is a major source of adipokines, inflammatory cytokines, or reactive oxidative species, which can… CONTINUE READING
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