Cardiac-Derived Extracellular Matrix Enhances Cardiogenic Properties of Human Cardiac Progenitor Cells.

@article{Gaetani2016CardiacDerivedEM,
  title={Cardiac-Derived Extracellular Matrix Enhances Cardiogenic Properties of Human Cardiac Progenitor Cells.},
  author={Roberto Gaetani and Christopher Yin and Neha Srikumar and Rebecca L. Braden and Pieter A.F.M. Doevendans and Joost P G Sluijter and Karen L Christman},
  journal={Cell transplantation},
  year={2016},
  volume={25 9},
  pages={
          1653-1663
        }
}
The use of biomaterials has been demonstrated as a viable strategy to promote cell survival and cardiac repair. However, limitations on combinational cell-biomaterial therapies exist, as cellular behavior is influenced by the microenvironment and physical characteristics of the material. Among the different scaffolds employed for cardiac tissue engineering, a myocardial matrix hydrogel has been shown to promote cardiogenesis in murine cardiac progenitor cells (mCPCs) in vitro. In this study, we… CONTINUE READING
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