Cardiac Conduction System Anomalies and Sudden Cardiac Death: Insights from Murine Models

Abstract

The cardiac conduction system (CCS) is composed of a group of myocardial tissues that control and coordinate the heart. Alterations in the CCS - especially in the His-Purkinje system, have been identified as a major cause of lethal arrhythmias. Unstable arrhythmias secondary to channelopathies significantly increase the risk of sudden cardiac death (SCD… (More)
DOI: 10.3389/fphys.2012.00211

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