Cardiac 3,4-dihydroxyphenylethylene glycol (DHPG) and catecholamine levels in a rat model of left ventricular failure.

@article{Howes1989Cardiac3G,
  title={Cardiac 3,4-dihydroxyphenylethylene glycol (DHPG) and catecholamine levels in a rat model of left ventricular failure.},
  author={Laurence Guy Howes and G. Peter Hodsman and C. Maccarrone and Masahiro Kohzuki and C. I. Johnston},
  journal={Journal of cardiovascular pharmacology},
  year={1989},
  volume={13 2},
  pages={
          348-52
        }
}
Cardiac norepinephrine (NE), dopamine (DA), epinephrine (Epi), and dihydroxyphenylethylene glycol (DHPG) (a major neuronal metabolite of NE) content were measured in rats with cardiac failure resulting from left ventricular myocardial infarction (LVMI) induced by coronary ligation. The ratio of DHPG/NE was significantly higher in both the right ventricle and interventricular septum of rats with LVMI compared with controls, reflecting a tendency for cardiac DHPG content to rise and NE content to… CONTINUE READING