Carcinostatic Action of Polycarbonyl Compounds and Their Derivatives II. Glyoxal Bis (Guanylhydrazone) and Derivatives

@article{Freedlander1958CarcinostaticAO,
  title={Carcinostatic Action of Polycarbonyl Compounds and Their Derivatives II. Glyoxal Bis (Guanylhydrazone) and Derivatives},
  author={B L Freedlander and F A French},
  journal={Cancer research},
  year={1958},
  volume={18 3},
  pages={
          360-3
        }
}
The authors have previously investigated the carcinostatic effect of simple hydrazine deriva tives. In early work (6, 7) acetic hydrazide and some methylated derivatives of formic hydrazide were found to have an inhibitory effect on mouse Adenocarcinoma 755. A number of substituted hydrazines and related compounds were also evaluated on myeloid mouse leukemia C1498 (8). The development of hydrazine derivatives of high antibacterial activity (1, 5) and the detection of antiviral activities in… CONTINUE READING

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American Association for Cancer cancerres.aacrjournals.org Downloaded from 1958;18:360-363

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B. L. FREEDLANDER, A. FÃœRST
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