Carcinoma showing thymus-like differentiation (CASTLE) with neuroendocrine differentiation.

  title={Carcinoma showing thymus-like differentiation (CASTLE) with neuroendocrine differentiation.},
  author={Manabu Yamazaki and Satoshi Fujii and Hiroyuki Daiko and R Hayashi and Atsushi Ochiai},
  journal={Pathology international},
  volume={58 12},
Carcinoma showing thymus-like differentiation (CASTLE) is a rare malignant neoplasm that histologically resembles thymic carcinoma and arises in the thyroid gland or adjacent soft tissue of the neck. Herein is reported the case of a 62-year-old male patient with CASTLE exhibiting neuroendocrine differentiation, who was treated with total pharyngolaryngo-esophagectomy and total thyroidectomy. Gross examination of the surgical specimen showed a grayish-white, solid, lobulated tumor, mainly… CONTINUE READING


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