Carcinoid tumors frequently display genetic abnormalities involving chromosome 11.

@article{Jakobovitz1996CarcinoidTF,
  title={Carcinoid tumors frequently display genetic abnormalities involving chromosome 11.},
  author={Orit Jakobovitz and D Nass and Laura Ann Demarco and Alfredo J.A. Barbosa and Frida Brok Simoni and Gideon Rechavi and Eitan R. Friedman},
  journal={The Journal of clinical endocrinology and metabolism},
  year={1996},
  volume={81 9},
  pages={
          3164-7
        }
}
Carcinoid tumors are neuroendocrine neoplasms that are encountered either sporadically or as part of a familial syndrome, most notably-multiple endocrine neoplasia type 1 (MEN1). The MEN1 gene localizes to chromosome 11 (11q13) and presumably functions as a tumor suppressor gene. The molecular mechanisms underlying carcinoid tumor development and their clonal composition remain largely unknown. To establish whether carcinoid tumors develop via a mechanism similar to other MEN1-associated tumors… CONTINUE READING
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