Carcinogenicity of radon/radon decay product inhalation in rats--effect of dose, dose rate and unattached fraction.

@article{Collier2005CarcinogenicityOR,
  title={Carcinogenicity of radon/radon decay product inhalation in rats--effect of dose, dose rate and unattached fraction.},
  author={Cathal Collier and Johnathon Strong and Jodie John Arthur Michael Humphreys and Nicholas J. Timpson and Shane T Baker and Tracy Eldred and L. Mason Cobb and D. Papworth and R. D. Haylock},
  journal={International journal of radiation biology},
  year={2005},
  volume={81 9},
  pages={631-47}
}
PURPOSE The effects of inhalation of radon/radon decay products at different total doses, dose rates and 'unattached' fractions were investigated in a life span study in rats. MATERIALS AND METHODS 1574 rats inhaled radon/radon decay products in a purpose-built recirculating exposure system that provided stable/reproducible exposure conditions. 501 were maintained as controls. RESULTS Lung tumour incidences were significantly elevated in most exposed groups. The study power was insufficient… CONTINUE READING