Carcinogenicity of lifelong administration of capsaicin of hot pepper in mice.

@article{Tth1992CarcinogenicityOL,
  title={Carcinogenicity of lifelong administration of capsaicin of hot pepper in mice.},
  author={B{\'e}la T{\'o}th and Peter M. Gannett},
  journal={In vivo},
  year={1992},
  volume={6 1},
  pages={59-63}
}
Capsaicin was administered in a semisynthetic powdered diet at 0.03125% level for the lifespan of Swiss mice starting from 6 weeks of age. As a result of C treatment, tumors of the cecum were induced in 22% of females and 14% of males, whereas the corresponding tumor incidences in untreated female and male controls were both 8%. Histopathologically, the tumors were classified as benign polypoid adenomas. Capsaicin is the main pungent principle of hot pepper, which is consumed in high quantities… CONTINUE READING

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