Corpus ID: 18988765

Carcinogenicity of dietary aflatoxin M1 in male Fischer rats compared to aflatoxin B1.

@article{Cullen1987CarcinogenicityOD,
  title={Carcinogenicity of dietary aflatoxin M1 in male Fischer rats compared to aflatoxin B1.},
  author={John M Cullen and Boris H. Ruebner and Li Shan Hsieh and Dallas M. Hyde and Dennis Paul Hsientang Hsieh},
  journal={Cancer research},
  year={1987},
  volume={47 7},
  pages={
          1913-7
        }
}
  • John M Cullen, Boris H. Ruebner, +2 authors Dennis Paul Hsientang Hsieh
  • Published in Cancer research 1987
  • Chemistry, Biology, Medicine
  • Aflatoxin M1 (AFM), an hydroxy metabolite of the potent carcinogenic mycotoxin aflatoxin B1 (AFB) is frequently found in milk and other dairy products. Sufficient amounts of AFM were produced to study the carcinogenicity of this compound. AFM was fed to male Fischer rats starting at 7 weeks up to 21 months of age. Agar-based semisynthetic diets contained 0.0, 0.5, 5.0, and 50.0 micrograms/kg of AFM or 50 micrograms/kg of AFB. Hepatocellular carcinomas were detected in two of 37 rats and… CONTINUE READING

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    Aflatoxin M1 levels in different marketed milk products in Nairobi, Kenya

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