Carcinogen adducts as an indicator for the public health risks of consuming carcinogen-exposed fish and shellfish.

  title={Carcinogen adducts as an indicator for the public health risks of consuming carcinogen-exposed fish and shellfish.},
  author={Bruce P Dunn},
  journal={Environmental Health Perspectives},
  pages={111 - 116}
  • Bruce P Dunn
  • Published 1991 in Environmental health perspectives
A large variety of environmental carcinogens are metabolically activated to electrophilic metabolites that can bind to nucleic acids and protein, forming covalent adducts. The formation of DNA-carcinogen adducts is thought to be a necessary step in the action of most carcinogens. Recently, a variety of new fluorescence, immunochemical, and radioactive-postlabeling procedures have been developed that allow the sensitive measurement of DNA-carcinogen adducts in organisms exposed to environmental… CONTINUE READING

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