Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis

@article{Beauchemin2013CarcinoembryonicAC,
  title={Carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) in cancer progression and metastasis},
  author={Nicole Beauchemin and Azadeh Arabzadeh},
  journal={Cancer and Metastasis Reviews},
  year={2013},
  volume={32},
  pages={643-671}
}
The discovery of the carcinoembryonic antigen (CEA) as a tumor marker for colorectal cancer some 50 years ago became the first step in the identification of a much larger family of 12 carcinoembryonic antigen-related cell adhesion molecules (CEACAMs) with surprisingly diverse functions in cell adhesion, in intracellular and intercellular signaling, and during complex biological processes such as cancer progression, inflammation, angiogenesis, and metastasis. The development of proper molecular… CONTINUE READING