Carcinoembryonic antigen: a useful prognostic marker in small-cell lung cancer.

  title={Carcinoembryonic antigen: a useful prognostic marker in small-cell lung cancer.},
  author={J. P. Sculier and Ron Feld and William K. Evans and Frances A. Shepherd and Gerrit E Deboer and D G Malkin and Aaron Malkin},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  volume={3 10},
Plasma carcinoembryonic antigen (CEA) was determined in 180 patients with small-cell lung cancer (SCLC) before treatment. An abnormal level (greater than or equal to 6 ng/mL) was found in 34% of patients tested. Patients with extensive disease (39/83) had a significantly higher frequency of abnormal CEA (P = .001) than those with limited disease (22/97). There was a strong correlation between obtaining an objective response--particularly a complete response (P = .00003)--and the absence of an… CONTINUE READING

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