Carcinoembryonic antigen, a tumor-associated glycoprotein induces defective lymphocyte function.

@article{Hakim1984CarcinoembryonicAA,
  title={Carcinoembryonic antigen, a tumor-associated glycoprotein induces defective lymphocyte function.},
  author={Anwar A. Hakim},
  journal={Neoplasma},
  year={1984},
  volume={31 4},
  pages={
          385-97
        }
}
Standard carcinoembryonic antigen(s) (CEA) obtained commercially, and CEA preparations from cell membranes and spent media of cultured human malignant melanotic melanoma (HMMC-ShAc and HMMC-ShAm) and of human colon adenocarcinomas (Levo c, Levo m, SW-403 c and SW-403 m) suppressed human peripheral blood lymphocyte (PBL). CEA preparations obtained from products of in vitro synthesis mediated by mRNA coding for CEA enhanced, whereas glycosylation-deficient preparations of CEA obtained from tumor… CONTINUE READING