Carboxypeptidase A: a protein and an enzyme.

@article{Quiocho1971CarboxypeptidaseAA,
  title={Carboxypeptidase A: a protein and an enzyme.},
  author={Florante A. Quiocho and William N. Lipscomb},
  journal={Advances in protein chemistry},
  year={1971},
  volume={25},
  pages={
          1-78
        }
}
  • Florante A. Quiocho, William N. Lipscomb
  • Published in Advances in protein chemistry 1971
  • Chemistry, Medicine
  • Publisher Summary This chapter discusses the relationship of the three-dimensional structures of bovine carboxypeptidase A (CPA), and of its complexes with substrates and inhibitors, to the functional behavior of this enzyme. In particular, it discusses the basis for substrate specificity, modes of binding, and possible mechanisms of hydrolytic cleavage of substrates for this enzyme. CPA is a zinc-containing proteolytic enzyme, which catalyzes the hydrolysis of carboxy-terminal peptide bonds in… CONTINUE READING

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