Carboxymethyl cellulose-hydroxyapatite hybrid hydrogel as a composite material for bone tissue engineering applications.

@article{Pasqui2014CarboxymethylCH,
  title={Carboxymethyl cellulose-hydroxyapatite hybrid hydrogel as a composite material for bone tissue engineering applications.},
  author={Daniela Pasqui and Paola Torricelli and Milena De Cagna and Milena Fini and Rolando Barbucci},
  journal={Journal of biomedical materials research. Part A},
  year={2014},
  volume={102 5},
  pages={1568-79}
}
Natural bone is a complex inorganic-organic nanocomposite material, in which hydroxyapatite (HA) nanocrystals and collagen fibrils are well organized into hierarchical architecture over several length scales. In this work, we reported a new hybrid material (CMC-HA) containing HA drown in a carboxymethylcellulose (CMC)-based hydrogel. The strategy for inserting HA nanocrystals within the hydrogel matrix consists of making the freeze-dried hydrogel to swell in a solution containing HA… CONTINUE READING

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