Carboxylesterase expression in human dental pulp cells: role in regulation of BisGMA-induced prostanoid production and cytotoxicity.

@article{Chang2012CarboxylesteraseEI,
  title={Carboxylesterase expression in human dental pulp cells: role in regulation of BisGMA-induced prostanoid production and cytotoxicity.},
  author={M. C. Chang and L Lin and F-H Chuang and C-P Chan and T Wang and J J Lee and P-Y Jeng and W Y Tseng and H Lin and J-H Jeng},
  journal={Acta biomaterialia},
  year={2012},
  volume={8 3},
  pages={1380-7}
}
Biocompatibility of dentin bonding agents (DBA) and composite resin may affect the treatment outcome (e.g., healthy pulp, pulpal inflammation, pulp necrosis) after operative restoration. Bisphenol-glycidyl methacrylate (BisGMA) is one of the major monomers present in DBA and resin. Prior studies focused on salivary esterase for metabolism and degradation of resin monomers clinically. This study found that human dental pulp cells expressed mainly carboxylesterase-2 (CES2) and smaller amounts of… CONTINUE READING

Connections & Topics

Mentioned Connections BETA
Addition of porcine esterase or N - acetyl - l - cysteine prevented BisGMA - induced prostaglandin E(2 ) ( PGE(2 ) ) and PGF(2α ) production .
All Topics