Carboxyl terminal of rhodopsin kinase is required for the phosphorylation of photo-activated rhodopsin

Abstract

Human rhodopsin kinase (RK) and a carboxyl terminus-truncated mutant RK lacking the last 59 amino acids (RKC) were expressed in human embryonic kidney 293 cells to investigate the role of the carboxyl terminus of RK in recognition and phosphorylation of rhodopsin. RKC, like the wild-type RK, was detected in both plasma membranes and cytosolic fractions. The… (More)
DOI: 10.1038/cr.1998.30

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